Zones of hyperalgesia of skin, associated with visceral disease. Due to referred sensation from the viscera, e.g. shoulder tip pain with gall bladder disease. In collateral irritation the organ disease causes a hyperaesthesia or pain in the skin areas whose nerves emanate from the same segment of the spinal marrow.

Through moxa, a certain region on the skin is stimulated with heat, which is connected with the somatic nervous system. The stimulation is directed to the brain, where specific organs are projected to specific dermatomes, areas on the skin